Other researchers suspect that not all the same genes affect male and female depression. While there's substantial overlap, says Kenneth Kendler, MD, a psychiatrist at Virginia Commonwealth University, there also "are genes that appear to act specifically in men but not women, and in women but not men." A number of researchers are now on the hunt for those genes.
Whether or not it turns out that men suffer more than the statistics show, there's no question many men are depressed. And just like women, all the experts agree, the longer they go without getting help, the stronger the negative impact on their lives.
Luckily, treatments are largely gender-blind. Though the older tricyclic drugs, like amitriptyline and imipramine, are slightly less effective in women than men, there's no such problem with the newer antidepressants like Prozac and its ilk. Most studies show that the many types of psychotherapy available can be equally beneficial for men and women.
Eric Weaver ultimately managed to put his illness behind him, but only after repeated hospitalizations, dozens of medications and, finally, an embrace of religion. Now retired from the police department, he is assistant pastor at his church. "I'm not saying I don't have bad days every once in a while," he says. "But now I can recognize it and deal with it."
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