50 Chemistry Pickup Lines Guaranteed to Get a Reaction

Updated: Mar. 18, 2024

These chemistry pickup lines will help you break the frozen H2O!

The scenario: You’re trying to impress your chemistry class crush or your significant other who appreciates science as much as you do. You’ve already memorized all these flirty knock-knock jokes and cheesy pickup lines, but you really want to show off some of the chemistry knowledge you’ve picked up over the years (who said all those chemistry courses went to waste?!). So you clicked on this story to give yourself some reaction-worthy chemistry pickup lines (reaction worthy, get it?) that anyone will appreciate.

Well, we have good news: You’re in the right place, and we have a plethora of pickup lines about chemistry for you to add to your list, especially if you’re a fan of chemistry jokes and puns too! These are pretty much guaranteed to get a chuckle out of your match, crush or significant other—even if they’re not chemistry nerds. (And if you don’t work in the science field, here’s the excuse you’ve been looking for to finally put all that chemistry knowledge to good use. Thank us later.)

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Periodic table chemistry pickup lines

Chemistry Pick Up Lines 1rd.com

1. Are you made of uranium and iodine? Because all I can see is U and I together.

2. You’re made of oxygen and neon, right? Because you’re definitely the ONe.

3. Are you made of copper? Because I can Cu in a relationship with me.

4. You must be a compound of barium and beryllium because you’re a total BaBe.

5. Are you made of fluorine, iodine and neon? Because you’re F-I-Ne.

6. You must be made of beryllium, gold and titanium because you’re BeAuTi-ful.

7. I wish I was adenine so I could get paired with U.

8. Scientists recently discovered a rare new element called beautium, and it looks like you’re made of it.

9. If you were an element you’d be francium because you’re the most attractive.

10. My favorite element is uranium because I love U.

11. Are you made of carbon? Because it feels like my world revolves around you.

12. My heart is made of gallium. It melts when you’re close to me.

13. Forget hydrogen, you’re my number one element.

14. Do you have 11 protons? Cause you’re sodium fine.

Chemical reaction pickup lines

Chemistry Pick Up Lines 2rd.com, Getty Images

15. Are you the acid to my litmus paper? Because every time I meet you I turn bright red.

16. I must be magnesium and you must be oxygen, because I light up when I’m with you.

17. You’re so hot you would make a nuclear reactor melt down.

18. I undergo anaerobic respiration when you’re near, because you take my breath away.

19. You’re hotter than sulfuric acid and sugar, and you smell twice as sweet.

20. You must have an extraordinary heat capacity, because you are hot!

21. I’m just hypothesizing, but I think the reaction between you and me would be quite exothermic. Care to plot some data points?

22. Is it cool if I stick to you like glue-cose?

23. Hey, want to swap oxidation numbers?

24. We must be galvanic cells, because there’s definitely electricity between us.

25. You’re like an exothermic reaction: You spread hotness everywhere.

Atomic and molecular chemistry pickup lines

Chemistry Pick Up Lines 3rd.com

26. Hey, want to get together sometime, since we both have unpaired electrons?

27. Excuse me, have you lost an electron? Because you are positively attractive!

28. Hey, I’ve got my ion you!

29. You’re a pretty perfect arrangement of atoms.

30. I’m so strongly attracted to you that scientists will have to discover a fifth fundamental force.

31. Are you a triple bond? Because you look like alkynes of fun.

32. We must have an ionic bond, because it’s difficult to break.

33. Could you tell me the oxidation state of this atom—and your phone number?

34. Are you an anion? Because I’m positive we’re meant to be together.

35. I might be a chemistry major, but I’d never Bohr you.

36. My favorite attractive force is van der Waal’s. Can you feel it? I’ll move closer if you can’t.

37. I wish your name was Avogadro because then I would already know your number.

38. We have such great chemistry that we should do some biology together.

Miscellaneous chemistry pickup lines

Chemistry Pick Up Lines 4rd.com, Getty Images

39. You’re the Higgs boson particle of my life … because without you, my universe wouldn’t “matter.”

40. According to the Second Law of Thermodynamics, you’re supposed to share your hotness with me.

41. Are you a non-volatile particle? Because you raise my boiling point.

42. So, what’s your quantum number?

43. Your PH must be 14, because you’re the most basic need in my life right now.

44. RNA is my favorite nucleic acid, because it has U in it.

45. You’re hotter than a Bunsen burner turned up all the way.

46. Quick! Get in the safety shower, because you’re on fire!

47. So, your lab or my lab?

48. Even the Kelvin scale couldn’t measure how hot you are.

49. My heart burns like a mole of suns for you.

50. Are you into science? Because I LAB you!