One of the most popular solutions for how to get rid of canker sores is baking soda. The powder is an alkaline and will neutralize acids that irritate the canker sore; it also helps kill bacteria to help provide canker sore relief. Try this home remedy: Rinse your mouth with a solution of 1 teaspoon baking soda in 1/2 cup of warm water.
Known as the “first-aid plant,” aloe vera gel can speed healing and offer soothing canker sore relief. Dry the canker sore area with a cotton swab, then slice an aloe leaf. With a clean spoon, dab a bit of the gel directly on the sore. Repeat as often as necessary. In addition to being one of the best canker sore remedies, aloe is also one of the most effective cold sore remedies.